Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN1 All Species: 15.76
Human Site: T353 Identified Species: 26.67
UniProt: Q16512 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16512 NP_002732.3 942 103932 T353 P S M G G P G T P D S R P P F
Chimpanzee Pan troglodytes XP_512443 1169 127241 T580 P S M G G P G T P D S R P P F
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 P421 A A A L A G S P S D G W L R T
Dog Lupus familis XP_542019 1076 118222 T486 P V A G V P G T P D S R T T F
Cat Felis silvestris
Mouse Mus musculus P70268 946 104392 T356 P S V G A S G T P E S R T P F
Rat Rattus norvegicus Q63433 946 104449 T356 P S V G A S G T P D S R T P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 P408 V A T V L G S P G E S R P W S
Chicken Gallus gallus XP_422357 1013 114806 T381 R S K A T S V T L P G W S P N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689331 948 107057 C366 G S Q V V L P C Y S P G E G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138 Q128 C P G M R D E Q P A K V E M V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 C201 I G K Q G Y Q C Q I C T V V V
Sea Urchin Strong. purpuratus XP_787090 799 90414 N260 K A R E L E I N V R W K D Q R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 N319 Q G W V N A S N I N G G S S L
Red Bread Mold Neurospora crassa P87253 1142 127954 Q407 P P S Q V V S Q P V D G W F N
Conservation
Percent
Protein Identity: 100 79.3 38.7 83 N.A. 91.6 91.9 N.A. 42.2 57.6 N.A. 66.7 N.A. 29 N.A. 27.8 48.5
Protein Similarity: 100 79.9 52.6 84.3 N.A. 94.7 94.6 N.A. 56.1 72.1 N.A. 79.5 N.A. 42.8 N.A. 43.4 61.7
P-Site Identity: 100 100 6.6 66.6 N.A. 66.6 73.3 N.A. 20 20 N.A. 6.6 N.A. 6.6 N.A. 6.6 0
P-Site Similarity: 100 100 13.3 66.6 N.A. 80 80 N.A. 33.3 20 N.A. 6.6 N.A. 6.6 N.A. 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.8 28.3
Protein Similarity: N.A. N.A. N.A. N.A. 44.4 45.1
P-Site Identity: N.A. N.A. N.A. N.A. 0 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 22 15 8 22 8 0 0 0 8 0 0 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 15 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 36 8 0 8 0 0 % D
% Glu: 0 0 0 8 0 8 8 0 0 15 0 0 15 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 36 % F
% Gly: 8 15 8 36 22 15 36 0 8 0 22 22 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 8 0 8 8 0 0 0 0 0 % I
% Lys: 8 0 15 0 0 0 0 0 0 0 8 8 0 0 0 % K
% Leu: 0 0 0 8 15 8 0 0 8 0 0 0 8 0 8 % L
% Met: 0 0 15 8 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 8 0 0 15 0 8 0 0 0 0 15 % N
% Pro: 43 15 0 0 0 22 8 15 50 8 8 0 22 36 0 % P
% Gln: 8 0 8 15 0 0 8 15 8 0 0 0 0 8 0 % Q
% Arg: 8 0 8 0 8 0 0 0 0 8 0 43 0 8 15 % R
% Ser: 0 43 8 0 0 22 29 0 8 8 43 0 15 8 8 % S
% Thr: 0 0 8 0 8 0 0 43 0 0 0 8 22 8 8 % T
% Val: 8 8 15 22 22 8 8 0 8 8 0 8 8 8 15 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 8 15 8 8 0 % W
% Tyr: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _